Histological page for infectious myonecrosis

Aquatic Animal Diseases Significant to Australia - Identification Field Guide 3rd edn

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Coagulative necrosis of skeletal muscle accompanied by haemocytic infiltration and fibrosis

Myonecrosis due to infection of Penaeus vannamei with purified virions.

(a) Coagulative necrosis of skeletal muscle accompanied by haemocytic infiltration and fibrosis. As a reference, normal skeletal muscle can be observed in the upper right corner. H&E stain; bar 50 ?m.

(b) Perinuclear pale basophilic to dark basophilic inclusion bodies are evident in this group of muscle cells (arrows point at some examples). H&E stain; bar 20 ?m.

(c) In situ hybridisation of skeletal muscle tissue using a digoxigenin-labelled infectious myonecrosis virus probe. A black precipitate is present in areas where the probe has hybridised with target virus. Bismarck brown counterstain; bar 50 ?m.
Source: DV Lightner

Perinuclear pale basophilic to dark basophilic inclusion bodies are evident in this group of muscle cells (arrows point at some examples)
Perinuclear pale basophilic to dark basophilic inclusion bodies are evident in this group of muscle cells (arrows point at some examples)